One lump or two?

Smallbone, Kieran (2009) One lump or two? [MIMS Preprint]

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We investigate methods for modelling metabolism within populations of cells. Typically one represents the interaction of a cloned population of cells with their environment as though it were one large cell. The question is as to whether any dynamics are lost by this assumption, and as to whether it might be more appropriate to instead model each cell individually. We show that it is sufficient to model at an intermediate level of granularity, representing the population as two interacting lumps of tissue.

Item Type: MIMS Preprint
Subjects: MSC 2010, the AMS's Mathematics Subject Classification > 34 Ordinary differential equations
MSC 2010, the AMS's Mathematics Subject Classification > 92 Biology and other natural sciences
Depositing User: Dr Kieran Smallbone
Date Deposited: 04 Dec 2009
Last Modified: 08 Nov 2017 18:18

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