State transitions in a model of intermittent seizure dynamics

Goodfellow, M and Rummel, C and Garry, D and Baier, G and Schindler, K and Glendinning, P (2012) State transitions in a model of intermittent seizure dynamics. [MIMS Preprint]

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Abstract

We present a neural mass model of intermittent transitions into electroencephalographic (EEG) seizure rhythms in epilepsy. The route to intermittent dynamics is identied as Type 1 and state transition statistics are explored. It is demonstrated that a single framework can give rise to different distributions for seizure and non-seizure lengths in line with variability observed clinically. Further investigation of this model can give insight into the possible mechanisms underlying spontaneous seizure transitions in the epileptic brain.

Item Type:	MIMS Preprint
Uncontrolled Keywords:	CICADA
Subjects:	PACS 2010, the AIP's Physics and Astronomy Classification Scheme > 80 INTERDISCIPLINARY PHYSICS AND RELATED AREAS OF SCIENCE AND TECHNOLOGY > 87 Biological and medical physics
Depositing User:	Professor Paul Glendinning
Date Deposited:	03 Aug 2012
Last Modified:	08 Nov 2017 18:18
URI:	https://eprints.maths.manchester.ac.uk/id/eprint/1853

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